(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and upper panels (D-K) showed that the opening of the AO connected to the right ventricle in the Gata4 haploinsufficency, while in control embryos the AO opened to the left ventricle. LV, left ventricle; RV, right ventricle; ao, aorta artery; pt, pulmonary trunk. Magnification: 40X (L-M) Blue ink stained embryo heart at E14.5. LV, left ventricle; RV, right ventricle; ao, aorta artery, pt, pulmonary trunk. Red arrow indicates the ink injected direction.</p
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
AbstractMembers of the GATA family of transcription factors are critical regulators of heart develop...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
(A-I’) Histology of Gata4 transgenic mouse embryo heart at E14.5. Two panel images of each embryonic...
Gata4 expression was detected in wildtype mouse embryos by IHC at (A) E9.5, (B) E10.5 and (C) E11.5....
(A-I) Histology of Gata4 transgenic mouse embryonic hearts at E14.5. Two panel images of each embryo...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
AbstractThe transcription factor Gata4 is essential for normal heart morphogenesis and regulates the...
The mammalian heart forms from multiple embryonic lineages whose specification and contributions to ...
Dominant mutations of Gata4, an essential cardiogenic transcription factor (TF), were known to cause...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
<p>Right (A,D,G), left (B,E,H) and frontal (C,F,I) views of embryos are shown. Growth retardation of...
(A-F) IHC staining for N-Cadherin in R26Rfl/+; Gata4fl/+ and R26Rfl/+; Gata4fl/+; Gli1-CreERT2/+ emb...
AbstractThe developing heart contains an inner tube of specialized endothelium known as endocardium,...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
AbstractMembers of the GATA family of transcription factors are critical regulators of heart develop...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
(A-I’) Histology of Gata4 transgenic mouse embryo heart at E14.5. Two panel images of each embryonic...
Gata4 expression was detected in wildtype mouse embryos by IHC at (A) E9.5, (B) E10.5 and (C) E11.5....
(A-I) Histology of Gata4 transgenic mouse embryonic hearts at E14.5. Two panel images of each embryo...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
AbstractThe transcription factor Gata4 is essential for normal heart morphogenesis and regulates the...
The mammalian heart forms from multiple embryonic lineages whose specification and contributions to ...
Dominant mutations of Gata4, an essential cardiogenic transcription factor (TF), were known to cause...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
<p>Right (A,D,G), left (B,E,H) and frontal (C,F,I) views of embryos are shown. Growth retardation of...
(A-F) IHC staining for N-Cadherin in R26Rfl/+; Gata4fl/+ and R26Rfl/+; Gata4fl/+; Gli1-CreERT2/+ emb...
AbstractThe developing heart contains an inner tube of specialized endothelium known as endocardium,...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
AbstractMembers of the GATA family of transcription factors are critical regulators of heart develop...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...