S on heart and liver development at st. 37. 50 ng of G4 MO () or 10 ng of G6 MO cause heart and liver defects. Similar defects are seen in embryos coinjected with 25 ng of G4 MO and 5 ng of G6 MOs (). 50 ng/embryo of C1 MO has no effect on heart and liver. -frequencies of the phenotypes observed. Heart and liver precursor have been analysed as in Fig. 1 with MLC2 and Hex markers.<p><b>Copyright information:</b></p><p>Taken from "GATA4 and GATA5 are essential for heart and liver development in embryos"</p><p>http://www.biomedcentral.com/1471-213X/8/74</p><p>BMC Developmental Biology 2008;8():74-74.</p><p>Published online 28 Jul 2008</p><p>PMCID:PMC2526999.</p><p></p
Congenital heart disease is the most common type of birth defect with an incidence of 1%. Previously...
(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and up...
Defects of atrial and ventricular septation are the most frequent form of congenital heart disease, ...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
Ected dose is indicated (in ng). 3–4–5, cDNA that contains exon 4 and regions of exons 3 and 5 deter...
Background: GATA factors 4/5/6 have been implicated in the development of the heart and endodermal ...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
Gata4 and Gata6 are closely related transcription factors that are essential for the development of ...
AbstractMembers of the GATA family of transcription factors are critical regulators of heart develop...
<p>(A) Embryonic lethality by E10.5 was found in compound heterozygote mice expressing only a <i>Gat...
Congenital heart disease is the most common type of birth defect with an incidence of 1%. Previously...
(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and up...
Defects of atrial and ventricular septation are the most frequent form of congenital heart disease, ...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
S of embryos injected with G5UTR MO or G4 MO are shown (50 ng/embryo). Heart and liver precursors ha...
H anti-HA antibody, is blocked by G4 but not by other MOs indicated. 1 ng of mRNA was injected into ...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
H anti-HA antibody, is blocked by G5 but not by other MOs indicated. G5UTR MO ("G5U") does not affec...
showed reduced expression), but not GATA4 MOs (19/19 embryos for G4 (50 ng) and 22/22 embryos for G4...
Ected dose is indicated (in ng). 3–4–5, cDNA that contains exon 4 and regions of exons 3 and 5 deter...
Background: GATA factors 4/5/6 have been implicated in the development of the heart and endodermal ...
AbstractNormal heart development is orchestrated by a set of highly conserved transcription factors ...
Gata4 and Gata6 are closely related transcription factors that are essential for the development of ...
AbstractMembers of the GATA family of transcription factors are critical regulators of heart develop...
<p>(A) Embryonic lethality by E10.5 was found in compound heterozygote mice expressing only a <i>Gat...
Congenital heart disease is the most common type of birth defect with an incidence of 1%. Previously...
(A-K’) Histology of Gata4 transgenic mouse embryonic heart at E14.5. The lower panels (A’-C’) and up...
Defects of atrial and ventricular septation are the most frequent form of congenital heart disease, ...