Sequence logos of PRE consensus motifs.

<p>The three known PRE motifs from TRANSFAC are shown in upper panels A (PR_01), B (PR_02), and C (PR_Q2). The consensus logo motifs derived using MEME analysis of ChIP-seq data from the 1,035 PR-binding sites common to both T47D breast cancer cells and leiomyoma cells are shown in lower panels of A, B, and C. Panel D shows the proposed consensus PRE motif based on the three TRANSFAC motifs and the discovered motifs from ChIP-seq data. For the consensus logos, the vertical axes (Bits) indicate the information content of the base frequency at that position. The horizontal axes refer to consensus site position.