<p><i>Notes: *</i> p<0.05 One way ANOVA lower in older animals. All variable interactions were not significant (p>0.05).</p><p><i>Abbreviations:</i> SNAP, synaptosome associated protein, Tg, transgenes.</p><p>Values are expressed as means ± SEM (n = 5–8 animals per group).</p
<p><b><i>A–D</i></b>, Hilar GABAergic interneurons positive for GAD67 (<b><i>A</i></b>), somatostati...
A. Representative sections from High-Active (left column) and Control (right column) mice. A section...
During brain development, the neocortex shows periods of enhanced plasticity, which enables the acqu...
<p>The synaptic proteins (A and B) SNAP-25, (C and D) synaptophysin, and (E and F) PSD-95 were measu...
Aging is associated with a general decline in cognitive functions, which appears to be due to altera...
Genetic disruption of synaptic proteins results in a whole variety of human neuropsychiatric disorde...
<p><b>A)</b> BDNF protein levels (measured with ELISA) in the hippocampus, frontal cortex, parietal ...
<p>Western blot showing α-synuclein protein in the striatum of young (A) and old (C) mice after sali...
The relative abundance of synaptic proteins shapes protein complex formation and is essential for sy...
The relative abundance of synaptic proteins shapes protein complex formation and is essential for sy...
<p>Illustration of sex-dependent changes in social interactions (A) and synaptic activity (B) in 12-...
<p>Western immunoblots showing tau accumulation with age as quantified in the TBS-soluble (soluble p...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
Development of the brain involves the formation and maturation of numerous synapses. This process re...
Development of the brain involves the formation and maturation of numerous synapses. This process re...
<p><b><i>A–D</i></b>, Hilar GABAergic interneurons positive for GAD67 (<b><i>A</i></b>), somatostati...
A. Representative sections from High-Active (left column) and Control (right column) mice. A section...
During brain development, the neocortex shows periods of enhanced plasticity, which enables the acqu...
<p>The synaptic proteins (A and B) SNAP-25, (C and D) synaptophysin, and (E and F) PSD-95 were measu...
Aging is associated with a general decline in cognitive functions, which appears to be due to altera...
Genetic disruption of synaptic proteins results in a whole variety of human neuropsychiatric disorde...
<p><b>A)</b> BDNF protein levels (measured with ELISA) in the hippocampus, frontal cortex, parietal ...
<p>Western blot showing α-synuclein protein in the striatum of young (A) and old (C) mice after sali...
The relative abundance of synaptic proteins shapes protein complex formation and is essential for sy...
The relative abundance of synaptic proteins shapes protein complex formation and is essential for sy...
<p>Illustration of sex-dependent changes in social interactions (A) and synaptic activity (B) in 12-...
<p>Western immunoblots showing tau accumulation with age as quantified in the TBS-soluble (soluble p...
<p>(A) Western blot analysis. Compared to the 4- and 8-week-old mice, LRG protein levels were higher...
Development of the brain involves the formation and maturation of numerous synapses. This process re...
Development of the brain involves the formation and maturation of numerous synapses. This process re...
<p><b><i>A–D</i></b>, Hilar GABAergic interneurons positive for GAD67 (<b><i>A</i></b>), somatostati...
A. Representative sections from High-Active (left column) and Control (right column) mice. A section...
During brain development, the neocortex shows periods of enhanced plasticity, which enables the acqu...