<p>Western blot showing α-synuclein protein in the striatum of young (A) and old (C) mice after saline or MPTP treatment. (B, D) Quantification of relative α-synuclein protein expression. Data presented are the means±SE. # p<0.05, significant differences between wild type and transgenic mice; n = 4−6 per group.</p
<p>Striata from wild type non-transgenic mice and A53T α-Syn mutant transgenic mice, 8 months of age...
The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the...
peer reviewedUnderstanding Parkinson’s disease (PD) in particular in its earliest phases, is importa...
<p>mThy1 and PDGF transgenic a-Synuclein mice and non transgenic littermates (n tg) are compared: (A...
Abstract Background Progressive accumulation of α-synuclein (α-Syn) protein in different brain regio...
<p>Transgenic mice expressing moderate levels (∼3-fold over endogenous levels) of wild type (WT, lin...
<p>Samples were collected at 1 day or 3 days from the striatum (A, B) and the substantia nigra (C, D...
α-Synuclein (αSN) in human is tightly linked both neuropathologically and genetically to Parkinson's...
The pathophysiological processes that cause Parkinson's disease (PD) affect dopamine neurons residin...
The pre-synaptic protein α-synuclein is the main component of Lewy bodies and Lewy neurites, the def...
α-Synuclein is an abundantly expressed neuronal protein that is at the center of focus in understand...
<p><b><i>A.</i></b> Expression of mouse and human α-synuclein in wild type (WT), mouse α-synuclein n...
<p>Representative immunoblots and densitometry analysis showing synaptophysin and PSD-95 levels in P...
The pathophysiological processes that cause Parkinson's disease (PD) affect dopamine neurons residin...
The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the...
<p>Striata from wild type non-transgenic mice and A53T α-Syn mutant transgenic mice, 8 months of age...
The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the...
peer reviewedUnderstanding Parkinson’s disease (PD) in particular in its earliest phases, is importa...
<p>mThy1 and PDGF transgenic a-Synuclein mice and non transgenic littermates (n tg) are compared: (A...
Abstract Background Progressive accumulation of α-synuclein (α-Syn) protein in different brain regio...
<p>Transgenic mice expressing moderate levels (∼3-fold over endogenous levels) of wild type (WT, lin...
<p>Samples were collected at 1 day or 3 days from the striatum (A, B) and the substantia nigra (C, D...
α-Synuclein (αSN) in human is tightly linked both neuropathologically and genetically to Parkinson's...
The pathophysiological processes that cause Parkinson's disease (PD) affect dopamine neurons residin...
The pre-synaptic protein α-synuclein is the main component of Lewy bodies and Lewy neurites, the def...
α-Synuclein is an abundantly expressed neuronal protein that is at the center of focus in understand...
<p><b><i>A.</i></b> Expression of mouse and human α-synuclein in wild type (WT), mouse α-synuclein n...
<p>Representative immunoblots and densitometry analysis showing synaptophysin and PSD-95 levels in P...
The pathophysiological processes that cause Parkinson's disease (PD) affect dopamine neurons residin...
The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the...
<p>Striata from wild type non-transgenic mice and A53T α-Syn mutant transgenic mice, 8 months of age...
The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the...
peer reviewedUnderstanding Parkinson’s disease (PD) in particular in its earliest phases, is importa...