NAb activities against HIV-1 pseudotyped viruses.

<p>Neutralization was shown as the percent inhibition of virus infection at 1∶20 dilution of the patient sera or using 10 µg/ml of monoclonal antibodies (b12, 2G12, and 4E10). “−“ indicates that percent of neutralization was below 50%. Percent of neutralization between 50–75% or greater than 75% are highlighted in yellow or red, respectively. The HIV-1 pseudotyped viruses used for neutralization assays are shown in the second row from top from “NL4-3” to “CM235.c11” with subtype indicated above the virus panel. “MuLV” is the murine leukemia virus used as negative control for neutralization assays. “NJ0XX”s in the far left column indicates individual patient serum samples; patient HIV subtypes are indicated above each group of samples. Known neutralizing monoclonal antibodies, IgG1 b12, 2G12 and 4E10, served as positive controls for neutralization assays.