Breadth of neutralization in HIV-1 subtype A infected patient sera.
- Peter Oballah (345671)
- Britta Flach (345673)
- Leigh A. Eller (345675)
- Michael A. Eller (204798)
- Benson Ouma (345678)
- Mark de Souza (289304)
- Hannah N. Kibuuka (345681)
- Fred Wabwire-Mangen (18024)
- Bruce K. Brown (171729)
- Nelson L. Michael (132309)
- Merlin L. Robb (132305)
- David Montefiori (161606)
- Victoria R. Polonis (132293)
Publication date
February 2013
DOIAbstract
<p>Shown is the breadth of neutralization for each serum sample against a panel of 10 pseudoviruses from five different subtypes (Purple columns = subtype CRF02_AG, yellow = subtype A, green = subtype B, blue = subtype C and orange = subtype D). Red boxes indicate ID<sub>50</sub>s>10 (positive neutralization). HIV-1 subtype A infected subjects showed more frequent neutralization against subtypes CRF02_AG and A, as compared to non-A subtypes (p<0.001, Fisher's exact test).</p
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