Effects of ESE-15-ol on mitochondrial membrane potential in MDA-MB-231, MCF-7 and MCF-12A cells after 24 h exposure.

<p>A) Flow cytometry histograms indicating relative fluorescence intensity for Mitocapture™ in the red channel (FL3 log). An increase in FL3 log indicates an increase in mitochondrial membrane depolarization and potential apoptosis. B) A statistically significant increase in mitochondrial membrane depolarization in the ESE-15-ol-treated cells compared to the vehicle-treated cells was observed across all three cell lines. * indicates a <i>P-</i>value <0.05 between vehicle-treated cells and ESE-16-treated cells.