TLR4 and CR3 blockade by anti-TLR4 and anti-CD11b antibodies modulated the cytokines production of <i>P. brasiliensis</i> infected A/J and B10.A macrophages.

<p>Macrophages from A/J and B10.A mice were untreated or treated with anti-TLR4 and anti-CD11b antibodies (10 µg/ml) for 30 min., infected or not with <i>P. brasiliensis</i> yeasts cells, and then cultivated for 48 h. The levels of cytokines were assessed by ELISA in the cell supernatants. Data are means ± SEM of triplicate samples from two experiment determinations. (*P<0.05, **P<0.01 and ***P<0.001).