<p>Bars represent levels of IL-12p40 (A and C) and IFN-γ (B and D) detected in the organs of mice from different experimental groups at 30 days post-infection. All immunized mice (Vaccine group) showed higher levels of IL-12 and IFN-γ, in both organs, when compared to controls (PBS). Data are representative of a typical experiment independently repeated three times, where: * P<0.05, and **P<0.01 in relation to the PBS Group.</p
<p>Spleen cells of mice of both sexes (n = 6) infected with <i>P.brasiliensis</i> yeast were collect...
<p>Macrophages from A/J and B10.A mice were untreated or treated with anti-TLR4 and anti-CD11b antib...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(<b>A, B</b>) At week 2 and 8 after i.t. infection with 1×10<sup>6</sup> yeast cells of <i>P. bra...
<p>BALB/c mice (seven/group) were infected with 1x10<sup>6</sup> of <i>P</i>. <i>brasiliensis</i> ye...
<p>Cytokine levels for TNF-α (A), IFN-γ (B), IL-1β (C), IL-6 (D), CXCL-1/KC (E) and CXCL-2/MIP-2 (F)...
<p>Mice were intraperitoneally infected with 5×10<sup>6</sup> yeasts cells and samples of their orga...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>At weeks 2 and 10 after i.t. infection with 1×10<sup>6</sup> yeast cells of <i>P. brasiliensis</i...
<p>Levels of cytokines detected upon intravenous infection of WT and TLR9<sup>−/−</sup> C57BL/6 mice...
<p>(A) IL-10<sup>−/−</sup> and WT mice were inoculated with 1×10<sup>6 </sup><i>P. brasiliensis</i> ...
<p>Levels of cytokines in lung homogenates of IL-10<sup>−/−</sup> and WT control mice were measured ...
<p>BALB/c mice were infected with 1.5x10<sup>6</sup> <i>P</i>. <i>brasiliensis</i> (Pb18) yeast cell...
*<p>Statistically significant difference (P<0.05) relative to mice infected with PbWT or PbEV.</p
<p>Male BALB/c mice (n = 5 mice/group for each analyses per experiment replicate) were inoculated wi...
<p>Spleen cells of mice of both sexes (n = 6) infected with <i>P.brasiliensis</i> yeast were collect...
<p>Macrophages from A/J and B10.A mice were untreated or treated with anti-TLR4 and anti-CD11b antib...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(<b>A, B</b>) At week 2 and 8 after i.t. infection with 1×10<sup>6</sup> yeast cells of <i>P. bra...
<p>BALB/c mice (seven/group) were infected with 1x10<sup>6</sup> of <i>P</i>. <i>brasiliensis</i> ye...
<p>Cytokine levels for TNF-α (A), IFN-γ (B), IL-1β (C), IL-6 (D), CXCL-1/KC (E) and CXCL-2/MIP-2 (F)...
<p>Mice were intraperitoneally infected with 5×10<sup>6</sup> yeasts cells and samples of their orga...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>At weeks 2 and 10 after i.t. infection with 1×10<sup>6</sup> yeast cells of <i>P. brasiliensis</i...
<p>Levels of cytokines detected upon intravenous infection of WT and TLR9<sup>−/−</sup> C57BL/6 mice...
<p>(A) IL-10<sup>−/−</sup> and WT mice were inoculated with 1×10<sup>6 </sup><i>P. brasiliensis</i> ...
<p>Levels of cytokines in lung homogenates of IL-10<sup>−/−</sup> and WT control mice were measured ...
<p>BALB/c mice were infected with 1.5x10<sup>6</sup> <i>P</i>. <i>brasiliensis</i> (Pb18) yeast cell...
*<p>Statistically significant difference (P<0.05) relative to mice infected with PbWT or PbEV.</p
<p>Male BALB/c mice (n = 5 mice/group for each analyses per experiment replicate) were inoculated wi...
<p>Spleen cells of mice of both sexes (n = 6) infected with <i>P.brasiliensis</i> yeast were collect...
<p>Macrophages from A/J and B10.A mice were untreated or treated with anti-TLR4 and anti-CD11b antib...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...