<p>The results were quantified by densitometry and normalized to the β-actin content. The data represent the means ± standard deviations from three independent experiments. The sign (*) represents a statistically significant difference (P-value <0.05) of caspase-2 enzyme activity in <i>Brucella</i>-infected BMDCs compared to uninfected control. A statistically significant difference of caspase-2 enzyme activities in RB51 or S2308-infected WT BMDCs was labeled with (**) (P-value <0.05).</p
<p>Macrophages were infected with <i>M. kansasii</i> in the presence or absence of the caspase-1 inh...
<p>(A) BMDM were infected with <i>L. monocytogenes</i> and gentamicin (480 Da) was added 30 min pi t...
<p>Calu-6 and THP-1 cells were incubated with inhibitors of MAPK pathways (PD: inhibitor of Erk1/2; ...
<p> To assess the effect of caspase-2 on DC function, the protein levels of TNF-α (A), IL-6 (B), IL1...
<p>(A) Analysis of caspase-2 activities by a colorimetric assay. The asterisk (*) represents signifi...
<p>WT or Casp2KO BMDCs were infected with S2308, RB51, or <i>S. typhimurium</i> strain SL1344 (MOI: ...
<p><b>A. Caspase 3/7 activity in BW720c-treated uninfected BL20 and infected TBL20.</b> Caspase 3/7 ...
<p>(<b>a</b>) Caspase-1 activity over the course of infection with <i>C. albicans</i>; absorbence of...
<p>(A) Recovery of bacteria post intracellular survival and growth in BMDCs. After infection of BMDC...
Smooth virulent Brucella abortus strain 2308 (S2308) causes zoonotic brucellosis in cattle and human...
<p>(A) BMDMs were left uninfected (U) or infected with <i>Y. pestis</i> strains expressing YopJ<sup>...
<p>(<b>a</b>) Caspase-8 activity after 60 Min stimulation of BMMs with <i>C. albicans</i> (Ca) or cu...
Smooth virulent Brucella abortus strain 2308 (S2308) causes zoonotic brucellosis in cattle and human...
<p>Five wild-type or IL-10 KO mice were infected i.p. with a dose of 10<sup>6</sup> CFU of <i>B. abo...
Mice spleens, livers and lungs were collected at days 1, 7, 21 and 28 after vaccination with live RB...
<p>Macrophages were infected with <i>M. kansasii</i> in the presence or absence of the caspase-1 inh...
<p>(A) BMDM were infected with <i>L. monocytogenes</i> and gentamicin (480 Da) was added 30 min pi t...
<p>Calu-6 and THP-1 cells were incubated with inhibitors of MAPK pathways (PD: inhibitor of Erk1/2; ...
<p> To assess the effect of caspase-2 on DC function, the protein levels of TNF-α (A), IL-6 (B), IL1...
<p>(A) Analysis of caspase-2 activities by a colorimetric assay. The asterisk (*) represents signifi...
<p>WT or Casp2KO BMDCs were infected with S2308, RB51, or <i>S. typhimurium</i> strain SL1344 (MOI: ...
<p><b>A. Caspase 3/7 activity in BW720c-treated uninfected BL20 and infected TBL20.</b> Caspase 3/7 ...
<p>(<b>a</b>) Caspase-1 activity over the course of infection with <i>C. albicans</i>; absorbence of...
<p>(A) Recovery of bacteria post intracellular survival and growth in BMDCs. After infection of BMDC...
Smooth virulent Brucella abortus strain 2308 (S2308) causes zoonotic brucellosis in cattle and human...
<p>(A) BMDMs were left uninfected (U) or infected with <i>Y. pestis</i> strains expressing YopJ<sup>...
<p>(<b>a</b>) Caspase-8 activity after 60 Min stimulation of BMMs with <i>C. albicans</i> (Ca) or cu...
Smooth virulent Brucella abortus strain 2308 (S2308) causes zoonotic brucellosis in cattle and human...
<p>Five wild-type or IL-10 KO mice were infected i.p. with a dose of 10<sup>6</sup> CFU of <i>B. abo...
Mice spleens, livers and lungs were collected at days 1, 7, 21 and 28 after vaccination with live RB...
<p>Macrophages were infected with <i>M. kansasii</i> in the presence or absence of the caspase-1 inh...
<p>(A) BMDM were infected with <i>L. monocytogenes</i> and gentamicin (480 Da) was added 30 min pi t...
<p>Calu-6 and THP-1 cells were incubated with inhibitors of MAPK pathways (PD: inhibitor of Erk1/2; ...