Role of MAPK pathways and NF-κB in CCL20 secretion by <i>Brucella</i>- infected lung epithelial cells and monocytes.

<p>Calu-6 and THP-1 cells were incubated with inhibitors of MAPK pathways (PD: inhibitor of Erk1/2; SB: inhibitor of p38 and SP: inhibitor of Jnk1/2) or NF-κB pathways (BAY) 1 h before the beginning of infection and kept throughout. Culture supernatants were harvested at 24 h post infection. NI: non-infected cells. Data are mean ± SEM of four independent experiments. Asterisks above bars indicate statistically significant differences (***, p < 0.001) relative to NI (ANOVA followed by Tukey’s Multiple Comparison test).