<p>(A) Analysis of caspase-2 activities by a colorimetric assay. The asterisk (*) represents significant differences (<i>P</i><0.05) compared to the medium control group. (B) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006830#s4f" target="_blank">Western blot analysis</a> of precaspase-2 in infected macrophages. The numbers shown in the figure represent the amounts of procaspase-2 quantified by densitometry and normalized to the β-actin content. The data represent the means±standard deviations from three independent experiments.</p
<p>BV2 microglia were treated or not with two different concentrations of neurotoxic prion peptides ...
<p>(<b>A</b>) THP-1 macrophages were infected with <i>M. kansasii</i> at an MOI of 1 for 1 h, before...
Cells were incubated under cell culture conditions with the indicated concentrations of ions in the ...
<p>Macrophages pretreated with Z-VDVAD-FMK were infected with RB51 for 24 h at a MOI of 200. (A) Mac...
<p>The results were quantified by densitometry and normalized to the β-actin content. The data repre...
<p>Macrophages were infected with <i>M. kansasii</i> in the presence or absence of the caspase-1 inh...
<p>(A) BMDMs were left uninfected (U) or infected with <i>Y. pestis</i> strains expressing YopJ<sup>...
<p>(A) Primary cultures of <i>Casp2<sup>+/+</sup></i> osteoclasts treated with 500 μM H<sub>2</sub>O...
<p>Peritoneal macrophages of BALB/c (left panel) or C57BL/6 mice (right panel) were infected or not ...
<p>Infection with S2308 at a MOI of 2,000 did not cause decrease of MMP or cytochrome <i>c</i> relea...
The figure shows Caspase 3/7 activation (columns) and cell viability (lines) in HeLa, Caco-2 and COL...
<p>BMDMs were seeded on glass coverslips in a 24-well plate and left uninfected (U) or infected with...
<p> To assess the effect of caspase-2 on DC function, the protein levels of TNF-α (A), IL-6 (B), IL1...
<p>A) A representative Western blot of procaspase and cleaved caspase-8 after 12 hours of treatments...
<p>(A) Cell death of RAW 264.7 cells at 6 hours post infection (hpi). The percentage of dead cells w...
<p>BV2 microglia were treated or not with two different concentrations of neurotoxic prion peptides ...
<p>(<b>A</b>) THP-1 macrophages were infected with <i>M. kansasii</i> at an MOI of 1 for 1 h, before...
Cells were incubated under cell culture conditions with the indicated concentrations of ions in the ...
<p>Macrophages pretreated with Z-VDVAD-FMK were infected with RB51 for 24 h at a MOI of 200. (A) Mac...
<p>The results were quantified by densitometry and normalized to the β-actin content. The data repre...
<p>Macrophages were infected with <i>M. kansasii</i> in the presence or absence of the caspase-1 inh...
<p>(A) BMDMs were left uninfected (U) or infected with <i>Y. pestis</i> strains expressing YopJ<sup>...
<p>(A) Primary cultures of <i>Casp2<sup>+/+</sup></i> osteoclasts treated with 500 μM H<sub>2</sub>O...
<p>Peritoneal macrophages of BALB/c (left panel) or C57BL/6 mice (right panel) were infected or not ...
<p>Infection with S2308 at a MOI of 2,000 did not cause decrease of MMP or cytochrome <i>c</i> relea...
The figure shows Caspase 3/7 activation (columns) and cell viability (lines) in HeLa, Caco-2 and COL...
<p>BMDMs were seeded on glass coverslips in a 24-well plate and left uninfected (U) or infected with...
<p> To assess the effect of caspase-2 on DC function, the protein levels of TNF-α (A), IL-6 (B), IL1...
<p>A) A representative Western blot of procaspase and cleaved caspase-8 after 12 hours of treatments...
<p>(A) Cell death of RAW 264.7 cells at 6 hours post infection (hpi). The percentage of dead cells w...
<p>BV2 microglia were treated or not with two different concentrations of neurotoxic prion peptides ...
<p>(<b>A</b>) THP-1 macrophages were infected with <i>M. kansasii</i> at an MOI of 1 for 1 h, before...
Cells were incubated under cell culture conditions with the indicated concentrations of ions in the ...