Location of PTPρ mutations.

<p>(<b>A</b>) Structure of PTPρ (PDB code 2OOQ) shown as a ribbon diagram. Mutated residues are highlighted in ball and stick and transparent cpk representation and are labelled in red. The active site cystein residue (C1106) is also shown and the catalytically important WPD loop is coloured in yellow. (<b>B</b>) Local environment of N1128. (<b>C</b>) Local environment of D927.