PSPA analysis shown as heat maps and sequence logos (prepared as in Fig 1) for WT (A) and the β3–αC loop mutant (B) of PKCβ. Numerical data are provided in S1 Data. PKC, protein kinase C; PSPA, positional scanning peptide array; WT, wild type.</p
a<p>Atomic coordinates of Protein Data Bank entry 2XE7;</p>b<p>atomic coordinates of Protein Data Ba...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
A crucial event in machinery controlled by Wnt signaling is the association of beta-catenin with the...
Mutants harbor residues found at the indicated positions in the other kinase as described in the mai...
(A) Quantified PSPA spot intensities were normalized to an average value of 1 at each position withi...
<p>(A) PKC-dependent (spots a and b: arrowheads) and -independent (spot c: arrow) phosphopeptide(s) ...
Distal interactions between discrete elements of an enzyme are critical for communication and ultima...
Regulation of Pak2 activity involves at least two mechanisms: (i) phosphorylation of the conserved T...
<p>The PCS activities of the single substitutions of the conserved residues on B-loop 1, B-loop 3, a...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
Six mutants of protein kinase CK2 alpha subunit in which basic residues have been mutated into alani...
Background: Distal interactions between discrete elements of an enzyme are critical for communicatio...
A crucial event in machinery controlled by Wnt signaling is the association of beta-catenin with the...
a<p>Atomic coordinates of Protein Data Bank entry 2XE7;</p>b<p>atomic coordinates of Protein Data Ba...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
A crucial event in machinery controlled by Wnt signaling is the association of beta-catenin with the...
Mutants harbor residues found at the indicated positions in the other kinase as described in the mai...
(A) Quantified PSPA spot intensities were normalized to an average value of 1 at each position withi...
<p>(A) PKC-dependent (spots a and b: arrowheads) and -independent (spot c: arrow) phosphopeptide(s) ...
Distal interactions between discrete elements of an enzyme are critical for communication and ultima...
Regulation of Pak2 activity involves at least two mechanisms: (i) phosphorylation of the conserved T...
<p>The PCS activities of the single substitutions of the conserved residues on B-loop 1, B-loop 3, a...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
Six mutants of protein kinase CK2 alpha subunit in which basic residues have been mutated into alani...
Background: Distal interactions between discrete elements of an enzyme are critical for communicatio...
A crucial event in machinery controlled by Wnt signaling is the association of beta-catenin with the...
a<p>Atomic coordinates of Protein Data Bank entry 2XE7;</p>b<p>atomic coordinates of Protein Data Ba...
The segment C-terminal to the hydrophobic motif at the V5 domain of protein kinase C (PKC) is the le...
A crucial event in machinery controlled by Wnt signaling is the association of beta-catenin with the...