Serum IgG against <i>S.</i> Paratyphi A FliC and LPS do not correlate with protection.

<p>(<b>A</b>) Total serum anti-FliC and anti-LPS ELISA antibody titers (geometric means ± standard error of the mean) from days −2 (prior to vaccination), 27 (two weeks following first boost) and 42 (two weeks following second boost). <i>S.</i> Paratyphi A FliC was extracted from strain CVD 1902. LPS was extracted from strain CVD 1901. (<b>B</b>) Comparison of anti-FliC and anti-LPS total serum IgG titers at day 42 from individual mice. Closed shapes represent mice that succumbed to the challenge.