Serum concentrations of human and mouse anti-F1 and anti-V mAbs in the plague mouse model over time.

<p>The same amount of human IgGs (500 µg) as used in the challenge studies were administered via i.p. and blood samples were collected at indicated time points. The human IgG concentration was determined by ELISA. The data shown are averages from three mice for each IgG. A. The amount of remaining human anti-F1 m252 and anti-V m254 in mouse serum. B. The amount of remaining mouse anti-F1 F1m and anti-V 7.3m in mouse serum.