<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and s (B). These profiles are defined in the extracellular medium () and distance is measured in the radial direction from the cell surface, i.e. . The 2D plots (not shown) viewed from the cell surface appear blue-red in (A) and red-blue in (B).</p
<p>(A) Illustration of the distance transform applied to cells in all colonies. Outside of the bound...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
We determine the ligand current into a single spherical cell which carries a large number of recepto...
<p>Ligand profiles computed as a function of distance at low cell density () for nM. The -values (s...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
<p>Spatial distribution of ligand computed at high (A, ) and low (B, ) cell densities. Note the diff...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
(a) Size of the ACs [50] and fit of the data to a Gaussian hill for ligand spacing of 50 nm (red), 1...
<p>The relation between the ligand concentration at the cell surface (C<sub>s</sub>) and the average...
<p>Here we assume a cubicle cellular configuration to match the shape frequently seen on epithelial ...
Interaction between biomaterials and cells is a critical aspect for successful application of tissue...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Circles are obtained from the simulation; the lines are guides to the eye. For this data, the sec...
<p>(A) Illustration of the distance transform applied to cells in all colonies. Outside of the bound...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
We determine the ligand current into a single spherical cell which carries a large number of recepto...
<p>Ligand profiles computed as a function of distance at low cell density () for nM. The -values (s...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
<p>Spatial distribution of ligand computed at high (A, ) and low (B, ) cell densities. Note the diff...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
(a) Size of the ACs [50] and fit of the data to a Gaussian hill for ligand spacing of 50 nm (red), 1...
<p>The relation between the ligand concentration at the cell surface (C<sub>s</sub>) and the average...
<p>Here we assume a cubicle cellular configuration to match the shape frequently seen on epithelial ...
Interaction between biomaterials and cells is a critical aspect for successful application of tissue...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Circles are obtained from the simulation; the lines are guides to the eye. For this data, the sec...
<p>(A) Illustration of the distance transform applied to cells in all colonies. Outside of the bound...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
We determine the ligand current into a single spherical cell which carries a large number of recepto...