<p>Ligand profiles computed as a function of distance at low cell density () for nM. The -values (s) are: a) 10; b) ; c) ; d) ; e) ; f) ; g) ; h) . These profiles are defined in the extracellular medium () and distance is defined as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021786#pone-0021786-g005" target="_blank">Fig.5</a>. The corresponding 2D plots (not shown) viewed from the cell surface appear blue-red.</p
We determine the ligand current into a single spherical cell which carries a large number of recepto...
(a) Size of the ACs [50] and fit of the data to a Gaussian hill for ligand spacing of 50 nm (red), 1...
<p>(A) For each inhibitor-bound pocket, the exemplar distance to the most similar pocket is indicate...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
<p>Spatial distribution of ligand computed at high (A, ) and low (B, ) cell densities. Note the diff...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
<p>Circles are obtained from the simulation; the lines are guides to the eye. For this data, the sec...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
<p> <b>cells/cm<sup>2</sup></b> (<b>a</b>) <b>and 10,000 cells/cm<sup>2</sup></b> (<b>b</b>) <b>at t...
(a) Reaction front propagation during staining of MFC10A cells with Hoechst dye. (b) Time traces of ...
<p>The <i>D</i> of Alexa488 dextran (10 kDa) was measured at various distances from the cell surface...
We determine the ligand current into a single spherical cell which carries a large number of recepto...
(a) Size of the ACs [50] and fit of the data to a Gaussian hill for ligand spacing of 50 nm (red), 1...
<p>(A) For each inhibitor-bound pocket, the exemplar distance to the most similar pocket is indicate...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
<p>Spatial distribution of ligand computed at high (A, ) and low (B, ) cell densities. Note the diff...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
<p>Circles are obtained from the simulation; the lines are guides to the eye. For this data, the sec...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
<p> <b>cells/cm<sup>2</sup></b> (<b>a</b>) <b>and 10,000 cells/cm<sup>2</sup></b> (<b>b</b>) <b>at t...
(a) Reaction front propagation during staining of MFC10A cells with Hoechst dye. (b) Time traces of ...
<p>The <i>D</i> of Alexa488 dextran (10 kDa) was measured at various distances from the cell surface...
We determine the ligand current into a single spherical cell which carries a large number of recepto...
(a) Size of the ACs [50] and fit of the data to a Gaussian hill for ligand spacing of 50 nm (red), 1...
<p>(A) For each inhibitor-bound pocket, the exemplar distance to the most similar pocket is indicate...