<p><i>Gne<sup>M712T/M712T</sup> (grey)</i> mouse muscle experienced reduced levels of GM3 gangliosides compared with <i>Gne<sup>+/+</sup> (white)</i> muscle. HPLC data from a minimum of five replicates are pooled for the <i>Gne<sup>+/+</sup></i> and <i>Gne<sup>M712T/M712T</sup></i> samples (*, <i>p = 0.008751, Student t test</i>).</p
(A) A synthetic pathway of gangliosides. Ganglioside species that are absent in KO mice for GM2S (β1...
<p>(A) Muscle lysates from G93A SOD1 mice (M) and non-transgenic littermates (W) were assessed for T...
<p>Analysis was performed in mice re-fed Chow diet (see <a href="http://www.plosone.org/article/info...
<p><i>Gne<sup>M712T/M712T</sup> (grey)</i> and <i>Gne<sup>+/+</sup> (white)</i> mouse kidney ganglio...
HIBM (Hereditary Inclusion Body Myopathy) is a recessive hereditary disease characterized by adult-o...
<p><i>A</i>, Comparison of GNE mRNA levels between <i>Gne<sup>+/+</sup> (diamond)</i> and <i>Gne<sup...
<p>Each graph depicts glucosylsphingosine levels in four tissues from mice having the same <i>Gba 1<...
<p>Means (± SEM) for (<b>A</b>) muscle glycogen concentration, determined using biochemical assays; ...
<p>(A) Soleus glycogen content. Soleus muscles were excised from 20 rpS6<sup>P+/+</sup> (WT) and 15 ...
<p>Tissue lysates were prepared for the indicated tissues from each mouse strain. Lysates from 5 mic...
<p>(<b>A</b>) GAA and glycogen levels were assessed in tissue lysates prepared from heart and gastro...
<p>(A) Wet weights of gastrocnemius muscles from 4 week-old <i>Hgs</i><sup><i>+/+</i></sup> and <i>H...
<p>Means (± SEM) for glycogen phosphorylase (<b>A</b>) and PKA activity (<b>B</b>) in skeletal muscl...
<p>Cerebrum, cerebellum or brain stem was isolated from 12-month-old WT, <i>Gnptab<sup>−/−</sup></i>...
<p>Immunoblots of muscle extracts from <i>Gne<sup>+/+</sup></i> and <i>Gne<sup>M712T/M712T</sup></i>...
(A) A synthetic pathway of gangliosides. Ganglioside species that are absent in KO mice for GM2S (β1...
<p>(A) Muscle lysates from G93A SOD1 mice (M) and non-transgenic littermates (W) were assessed for T...
<p>Analysis was performed in mice re-fed Chow diet (see <a href="http://www.plosone.org/article/info...
<p><i>Gne<sup>M712T/M712T</sup> (grey)</i> and <i>Gne<sup>+/+</sup> (white)</i> mouse kidney ganglio...
HIBM (Hereditary Inclusion Body Myopathy) is a recessive hereditary disease characterized by adult-o...
<p><i>A</i>, Comparison of GNE mRNA levels between <i>Gne<sup>+/+</sup> (diamond)</i> and <i>Gne<sup...
<p>Each graph depicts glucosylsphingosine levels in four tissues from mice having the same <i>Gba 1<...
<p>Means (± SEM) for (<b>A</b>) muscle glycogen concentration, determined using biochemical assays; ...
<p>(A) Soleus glycogen content. Soleus muscles were excised from 20 rpS6<sup>P+/+</sup> (WT) and 15 ...
<p>Tissue lysates were prepared for the indicated tissues from each mouse strain. Lysates from 5 mic...
<p>(<b>A</b>) GAA and glycogen levels were assessed in tissue lysates prepared from heart and gastro...
<p>(A) Wet weights of gastrocnemius muscles from 4 week-old <i>Hgs</i><sup><i>+/+</i></sup> and <i>H...
<p>Means (± SEM) for glycogen phosphorylase (<b>A</b>) and PKA activity (<b>B</b>) in skeletal muscl...
<p>Cerebrum, cerebellum or brain stem was isolated from 12-month-old WT, <i>Gnptab<sup>−/−</sup></i>...
<p>Immunoblots of muscle extracts from <i>Gne<sup>+/+</sup></i> and <i>Gne<sup>M712T/M712T</sup></i>...
(A) A synthetic pathway of gangliosides. Ganglioside species that are absent in KO mice for GM2S (β1...
<p>(A) Muscle lysates from G93A SOD1 mice (M) and non-transgenic littermates (W) were assessed for T...
<p>Analysis was performed in mice re-fed Chow diet (see <a href="http://www.plosone.org/article/info...