Altered glycogen metabolism contributes to the increased muscle glycogen concentration in <i>mdx</i> mice.

<p>Means (± SEM) for glycogen phosphorylase (<b>A</b>) and PKA activity (<b>B</b>) in skeletal muscles from BL10 wild type and <i>mdx</i>. n = 8; **<i>P</i> = 0.01 compared with skeletal muscle from BL/10 wild type mice. Means (± SEM) for glycogen branching enzyme (GBE, <b>C</b>) and glycogen debranching enzyme (GDE, <b>D</b>) activity in skeletal muscle from BL10 wild type and <i>mdx</i> mice. Protein expression was detected by immunoblot and its relative level of expression normalized against GAPDH. Data represented as ± SEM, n = 8; ***<i>P</i> = 0.001 compared with skeletal muscle from BL/10 wild type mice. Means (± SEM) for starch-binding domain containing protein 1 (STBD1) protein (<b>E</b>) and mRNA (<b>F</b>) expression relative to GAPDH or cDNA content, respectively. **<i>P</i><0.01 compared with skeletal muscle from BL/10 wild type mice.