Lung mechanics after silica injury.

<p>Changes in lung mechanics were similar in WT and RAGE KO mice. Closed bars represent silica treatment and open bars vehicle control. (A) While the airway resistance in silica treated WT mice was not significantly increased over control, the RAGE KO mice treated with silica had a significant increase. All other values (B–E) were significantly changed for both WT and RAGE KO; however there were no other significant differences between WT and RAGE KO. Data are means (±SEM) analyzed by 2-way ANOVA with a Bonferroni post-test. (<i>n = 5–6 per group</i>). * p<0.05 silica vs. control.