<p><i>A</i>, lung static elastance (Est); <i>B</i>, viscoelastic component of elastance (ΔE); <i>C</i> - <i>E</i>, resistive (ΔP1), viscoelastic/inhomogeneous (ΔP2), and total lung pressures (ΔPtot), respectively in wild-type (WT) and P2X7 receptor knockout (KO) animals. Values represent mean + SEM of 6–9 animals/group (10 determinations per animal). *p <0.05 and **p <0.001 in relation to the respective control (CTRL).</p
Respiratory system resistance (R) and elastance (E) are commonly estimated by fitting the linear equ...
Introduction: Mouse models of emphysema are important tools for testing different therapeutic strate...
Abstract This study was undertaken to determine whether a smaller lung volume or a stiffer lung tiss...
<p>Representative lung parenchyma photomicrographs (hematoxylin-eosin staining) of: <i>A</i> and <i>...
<p>(<b>A</b>) Resistance (ΔP1,l) and viscoelastic (ΔP2,l) pressures and (<b>B</b>) lung static elast...
<p>Plethysmography was performed at 12 weeks on anesthetized mutant mice and littermate controls. (A...
<p>(A) Static (E<sub>st</sub>) and (B) dynamic (E<sub>dyn</sub>) elastances in WT (white column) and...
<p>(A) Static (E<sub>st</sub>) and (B) dynamic (E<sub>dyn</sub>) elastances in WT (white column) and...
<p>Changes in lung mechanics were similar in WT and RAGE KO mice. Closed bars represent silica treat...
<p>Photomicrographs of lung parenchyma of wild-type mice 14 days after intratracheal instillation of...
Mice are increasingly used as models of lung disease and are an important tool for improving our und...
<p>Photomicrographs of lung parenchyma of wild-type (<i>A, B, E</i>) and P2X7 receptor knockout (<i>...
lished October 9, 2008; doi:10.1152/japplphysiol.90924.2008.—Ab-solute lung volumes such as function...
The study aim was to establish how recruitment maneuvers (RMs) influence lung mechanics and to deter...
Respiratory pathologies alter the structure of the lung and impact its mechanics. Mice are widely us...
Respiratory system resistance (R) and elastance (E) are commonly estimated by fitting the linear equ...
Introduction: Mouse models of emphysema are important tools for testing different therapeutic strate...
Abstract This study was undertaken to determine whether a smaller lung volume or a stiffer lung tiss...
<p>Representative lung parenchyma photomicrographs (hematoxylin-eosin staining) of: <i>A</i> and <i>...
<p>(<b>A</b>) Resistance (ΔP1,l) and viscoelastic (ΔP2,l) pressures and (<b>B</b>) lung static elast...
<p>Plethysmography was performed at 12 weeks on anesthetized mutant mice and littermate controls. (A...
<p>(A) Static (E<sub>st</sub>) and (B) dynamic (E<sub>dyn</sub>) elastances in WT (white column) and...
<p>(A) Static (E<sub>st</sub>) and (B) dynamic (E<sub>dyn</sub>) elastances in WT (white column) and...
<p>Changes in lung mechanics were similar in WT and RAGE KO mice. Closed bars represent silica treat...
<p>Photomicrographs of lung parenchyma of wild-type mice 14 days after intratracheal instillation of...
Mice are increasingly used as models of lung disease and are an important tool for improving our und...
<p>Photomicrographs of lung parenchyma of wild-type (<i>A, B, E</i>) and P2X7 receptor knockout (<i>...
lished October 9, 2008; doi:10.1152/japplphysiol.90924.2008.—Ab-solute lung volumes such as function...
The study aim was to establish how recruitment maneuvers (RMs) influence lung mechanics and to deter...
Respiratory pathologies alter the structure of the lung and impact its mechanics. Mice are widely us...
Respiratory system resistance (R) and elastance (E) are commonly estimated by fitting the linear equ...
Introduction: Mouse models of emphysema are important tools for testing different therapeutic strate...
Abstract This study was undertaken to determine whether a smaller lung volume or a stiffer lung tiss...