Glucose tolerance test in control or streptozotocin (STZ)-treated OX^−/− and C57BL/6 mice.

<p>The graph shows blood glucose levels in control or STZ-treated OX^−/− and C57BL/6 mice 0, 30, 60 and 180 min after intra-peritoneal glucose challenge (3 g/kg body weight, given intra-peritoneally). Blood glucose levels of control OX^−/− and C57BL/6 mice were similar at time 0, 30, 60, 180 min. Note that blood glucose level of STZ-induced diabetic OX^−/− mice was slightly but not significantly lower than that of diabetic C57BL/6 mice at 0 min. Diabetic OX^−/− mice displayed a significantly (<i>p</i><0.01) lower blood glucose levels compared to those of diabetic wild type at 60 and 180 min after glucose load.