Model interpretation, known mutations that lead to NNRTI (cross) resistance.
- Gerard J. P. van Westen (195154)
- Alwin Hendriks (381073)
- Jörg K. Wegner (195157)
- Adriaan P. IJzerman (195167)
- Herman W. T. van Vlijmen (195170)
- Andreas Bender (192334)
Publication date
February 2013
DOIAbstract
<p>The pattern produced by our model correlates with literature. <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002899#pcbi.1002899-Johnson1" target="_blank">[6]</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002899#pcbi.1002899-ShaferRobert1" target="_blank">[18]</a> In particular the specific profiles of V106I, Y181C and G190A are reproduced well. Values in the cells represent Log FC.</p
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