<p>Decrease in the log<sub>10</sub> CFU counts in the footpads of mice treated with, streptomycin+ rifampin for 5 days a week (STR+RIF 5/7), STR+RIF for 7 days a week (STR+RIF 7/7) and STR+ rifapentine (RPT) (STR+RPT 5/7) compared to untreated controls. The day after infection counts are shown at −25 (Mice were infected at D-26) and treatment was started after 25 days (D0).</p
Mice were infected with M. ulcerans 1059AL. After 5 weeks the swelling grade was nearly 2 on a scale...
<p><b>A</b>: Relative lung weights were calculated as a percentage of total body mass (mean +− SE). ...
BALB/c mice were inoculated in their footpad with L. major. After 21 days, mice were treated i.p. wi...
<p>Mean CFU count from mouse footpads on the day after infection (Day1), the day of treatment initia...
<p>After infection in the right hind footpad (RHFP), there were increases in the numbers of <i>M. ul...
<p>Beginning 11 days post-infection, mice received monotherapy with different doses of RIF (red), ST...
<p><b>(A) Footpad swelling</b>. After infection of both hind footpads, treatment began when swelling...
<p>Kaplan-Meier curve depicting the percentage of mice free of footpad swelling during 39 weeks of f...
<p>Mice were randomized after infection with 0.03 ml of an inoculum containing 6.06 log<sub>10</sub>...
<p>The number in parenthesis indicates the number of mice kept for footpad swelling.</p><p>D-25 is t...
<p>Due to animal welfare reasons, mice were sacrificed early as explained in text.</p><p>D, day; w, ...
<p>The mice were treated with RIF (red), STR (green) and CLR (blue) alone. Untreated (black). (A, D,...
<p>After 3 days of RIF-STR (RS) treatment (day 27 after infection), swelling averaged grade 1, and t...
disease, or Buruli ulcer, has shifted from surgery to daily treatment with streptomycin (STR) + rif...
<p>After infection in the right hind footpad (RHFP), grade 1 swelling was first detected at 5 weeks....
Mice were infected with M. ulcerans 1059AL. After 5 weeks the swelling grade was nearly 2 on a scale...
<p><b>A</b>: Relative lung weights were calculated as a percentage of total body mass (mean +− SE). ...
BALB/c mice were inoculated in their footpad with L. major. After 21 days, mice were treated i.p. wi...
<p>Mean CFU count from mouse footpads on the day after infection (Day1), the day of treatment initia...
<p>After infection in the right hind footpad (RHFP), there were increases in the numbers of <i>M. ul...
<p>Beginning 11 days post-infection, mice received monotherapy with different doses of RIF (red), ST...
<p><b>(A) Footpad swelling</b>. After infection of both hind footpads, treatment began when swelling...
<p>Kaplan-Meier curve depicting the percentage of mice free of footpad swelling during 39 weeks of f...
<p>Mice were randomized after infection with 0.03 ml of an inoculum containing 6.06 log<sub>10</sub>...
<p>The number in parenthesis indicates the number of mice kept for footpad swelling.</p><p>D-25 is t...
<p>Due to animal welfare reasons, mice were sacrificed early as explained in text.</p><p>D, day; w, ...
<p>The mice were treated with RIF (red), STR (green) and CLR (blue) alone. Untreated (black). (A, D,...
<p>After 3 days of RIF-STR (RS) treatment (day 27 after infection), swelling averaged grade 1, and t...
disease, or Buruli ulcer, has shifted from surgery to daily treatment with streptomycin (STR) + rif...
<p>After infection in the right hind footpad (RHFP), grade 1 swelling was first detected at 5 weeks....
Mice were infected with M. ulcerans 1059AL. After 5 weeks the swelling grade was nearly 2 on a scale...
<p><b>A</b>: Relative lung weights were calculated as a percentage of total body mass (mean +− SE). ...
BALB/c mice were inoculated in their footpad with L. major. After 21 days, mice were treated i.p. wi...