Border progression.

<p>Experiments (left column: A,C,E,G) and numerical simulations (right column : B,D,F,H). The model parameters are the same as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002944#pcbi-1002944-g003" target="_blank">Figure 3</a>. Pictures of the epithelium at ((A), (B)), ((C),(D)) and ((E),(F)). In the experimental pictures (A,C,E) the cells are shown. For the simulation, the positions of the particles are shown as black dots. (G) mean border progression in (n = 6) experiments shown as colored triangles; the average progression is shown as a solid black line together with a quadratic fit at early times () and a linear fit at late times ()(dashed light blue lines) (H) mean border progression in (n = 6) simulations shown as colored squares; the average progression is shown as a solid black line together with a quadratic fit at early times () and a linear fit at late times () (dashed light blue lines). In the simulations, cell division was implemented, as described in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002944#s4" target="_blank"><i>Methods</i></a>.