The cross-section of a cell in a monolayer epithelial tissue can be modeled mathematically as a k-sided polygon. Empirically studied distributions of the proportions of k-sided cells in epithelia show remarkable similarities in a wide range of evolutionarily distant organisms. A variety of mathematical models have been proposed for explaining this phenomenon. The highly parsimonious simulation model of (Patel et al., PLoS Comput. Biol., 2009) that takes into account only the number of sides of a given cell and cell division already achieves a remarkably good fit with empirical distributions from Drosophila, Hydra, Xenopus, Cucumber, and Anagallis. Within the same modeling framework as in that paper, we introduce additional options for...
The development of multicellular organisms is accompanied by the formation of tis- sues of precise s...
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simul...
<p>(A) - (C) The epithelial cell area distribution for each model – the red curve marks the fitted G...
The cross-section of a cell in a monolayer epithelial tissue can be modeled mathematically as a k-si...
The cross-section of a cell in a monolayer epithelial tissue can be modeled mathematically as a k-si...
International audienceUnderstanding the mechanisms regulating development requires a quantitative ch...
Morphogenesis - the generation of biological shape and form - is fascinating, and its study promises...
Cell proliferation affects both cellular geometry and topology in a growing tissue, and hence rules ...
International audienceThe physical laws governing the morphogenesis of biological tissues remain lar...
Invitation to a keynote lecture (by Taiji Adachi and Dimitrije Stamenovic) for the session "Computat...
<div><p>Geometric and mechanical properties of individual cells and interactions among neighboring c...
Organ and tissue formation are complex three-dimensional processes involving cell division, growth, ...
BACKGROUND: Epithelial junctional networks assume packing geometries characterized by different cell...
Geometric order in quasi-two-dimensional epithelia has been extensively researched in order to ident...
Understanding the cellular organization of tissues is key to developmental biology. In order to deal...
The development of multicellular organisms is accompanied by the formation of tis- sues of precise s...
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simul...
<p>(A) - (C) The epithelial cell area distribution for each model – the red curve marks the fitted G...
The cross-section of a cell in a monolayer epithelial tissue can be modeled mathematically as a k-si...
The cross-section of a cell in a monolayer epithelial tissue can be modeled mathematically as a k-si...
International audienceUnderstanding the mechanisms regulating development requires a quantitative ch...
Morphogenesis - the generation of biological shape and form - is fascinating, and its study promises...
Cell proliferation affects both cellular geometry and topology in a growing tissue, and hence rules ...
International audienceThe physical laws governing the morphogenesis of biological tissues remain lar...
Invitation to a keynote lecture (by Taiji Adachi and Dimitrije Stamenovic) for the session "Computat...
<div><p>Geometric and mechanical properties of individual cells and interactions among neighboring c...
Organ and tissue formation are complex three-dimensional processes involving cell division, growth, ...
BACKGROUND: Epithelial junctional networks assume packing geometries characterized by different cell...
Geometric order in quasi-two-dimensional epithelia has been extensively researched in order to ident...
Understanding the cellular organization of tissues is key to developmental biology. In order to deal...
The development of multicellular organisms is accompanied by the formation of tis- sues of precise s...
We investigate morphologies of proliferating cellular tissue using a newly developed numerical simul...
<p>(A) - (C) The epithelial cell area distribution for each model – the red curve marks the fitted G...