<p>Fit of the coinfection model (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat.1003238.e183" target="_blank">Equations (6)</a>–<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat.1003238.e187" target="_blank">(10)</a>) to viral (panel A) and bacterial (panel B) lung titers from individual mice infected with PR8 virus followed 7 days later by 1000 CFU <i>S. pneumoniae</i> strain D39. Parameters for the model curves are in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat-1003238-t001" target="_blank">Tables 1</a>–<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat-1003238-t002" target="_...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...
<p>Eight to twelve weeks old mice were infected intra-nasally with 2×10<sup>5</sup> FFU of PR8M viru...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>Fit of the coinfection model (<a href="http://www.plospathogens.org/article/info:doi/10.1371/jour...
<p>Numerical simulation of the coinfection model, <a href="http://www.plospathogens.org/article/info...
(A-B) Viral and bacterial titers in whole lung homogenates of coinfected mice on day 9 (day 2 after ...
<p>Maximum likelihood fits of the viral kinetic model (<b>Equations (4)</b>–<b>(7)</b>) to lung tite...
<p>Individual (black dots) and average (colored boxes/triangles) values of bacterial titers to illu...
<p>Mice were challenged with D39, D39Δ<i>spd1837</i>, D39Spd1837<sub>C8S,</sub> D39Δ<i>spd1838</i>, ...
<p>Mice immunized IN with designed doses of VLPs were challenged with a lethal dose (40 LD<sub>50</s...
Improvements to viral diagnostic techniques led to increased detection of multiple respiratory viral...
<p>Young control mice (n = 5) and <i>Foxn1 K14</i>KO mice (n = 5) were infected with 0.2 LD50 of PR8...
<p>Mice were infected with sub-lethal dose of PR8 by intra-tracheal inhalation. <b>A.</b> PR8 replic...
<p><b>A.</b> Competition between strain PMM99 and wild-type <i>M. bovis</i> BCG in infected SCID mic...
<p>Bacterial propagation in the lungs of C57BL/6J mice infected i.n. with 1x10<sup>5</sup> cfu of th...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...
<p>Eight to twelve weeks old mice were infected intra-nasally with 2×10<sup>5</sup> FFU of PR8M viru...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>Fit of the coinfection model (<a href="http://www.plospathogens.org/article/info:doi/10.1371/jour...
<p>Numerical simulation of the coinfection model, <a href="http://www.plospathogens.org/article/info...
(A-B) Viral and bacterial titers in whole lung homogenates of coinfected mice on day 9 (day 2 after ...
<p>Maximum likelihood fits of the viral kinetic model (<b>Equations (4)</b>–<b>(7)</b>) to lung tite...
<p>Individual (black dots) and average (colored boxes/triangles) values of bacterial titers to illu...
<p>Mice were challenged with D39, D39Δ<i>spd1837</i>, D39Spd1837<sub>C8S,</sub> D39Δ<i>spd1838</i>, ...
<p>Mice immunized IN with designed doses of VLPs were challenged with a lethal dose (40 LD<sub>50</s...
Improvements to viral diagnostic techniques led to increased detection of multiple respiratory viral...
<p>Young control mice (n = 5) and <i>Foxn1 K14</i>KO mice (n = 5) were infected with 0.2 LD50 of PR8...
<p>Mice were infected with sub-lethal dose of PR8 by intra-tracheal inhalation. <b>A.</b> PR8 replic...
<p><b>A.</b> Competition between strain PMM99 and wild-type <i>M. bovis</i> BCG in infected SCID mic...
<p>Bacterial propagation in the lungs of C57BL/6J mice infected i.n. with 1x10<sup>5</sup> cfu of th...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...
<p>Eight to twelve weeks old mice were infected intra-nasally with 2×10<sup>5</sup> FFU of PR8M viru...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...