Coinfection model fit to lung titers of mice coinfected with PR8-PB1-F2(1918) and 1000 CFU D39.

<p>Fit of the coinfection model (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat.1003238.e183" target="_blank">Equations (6)</a>–<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat.1003238.e187" target="_blank">(10)</a>) to viral (panel A) and bacterial (panel B) lung titers from individual mice infected with PR8-PB1-F2(1918) virus followed 7 days later by 1000 CFU <i>S. pneumoniae</i> strain D39. Parameters for the model curves are in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat-1003238-t001" target="_blank">Tables 1</a>–<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003238#ppat-1003238-t002" target="_blank">2</a>.