<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K627E</sub> (□), Ts<sub>E627</sub> (▾), and rTs<sub>E627K</sub> (∇). Lungs from three mice per virus group per time point were harvested and homogenized in 1 ml of PBS. Cytokine levels were measured individually and in duplicate. Baseline cytokine levels from PBS inoculated mice (n = 5) are shown as a dashed line in each cytokine graph. The data shown represents mean ± SD for three independent experiments. <b>*</b><i>p</i><0.05 between V<sub>K627</sub> and rV<sub>K627E</sub>; <b>ˆ</b><i>p</i><0.05 between Ts<sub>E627</sub> and rTs<sub>E627K</sub>.</p
<p>Lung levels of TNF-α (A and B), IL-1β (C and D) and IL-6 (E and F) of wild type (WT, black bars) ...
<div><p>(A) IFN-γ enzyme-linked immunosorbent assay was performed on lung homogenates with four mice...
<p>Mice were infected intranasally with 5×10<sup>7</sup> CFU WT GBS and cytokine levels in cell-free...
<p>Cytokine levels from infected lungs (n = 3 mice per virus group, days 1 and 4 post-inoculation (p...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>Groups of three BALB/c mice were inoculated intranasally with 10<sup>5</sup> pfu of SD16 or SD16-...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>C57BL/6 (B6) or B6.C3H-<i>sst1</i> congenic mice were infected with <i>C. pneumoniae</i> (Cp) as ...
<p>Mice were euthanized at indicated times p.i. The collected lungs were weighed, and 10% homogenate...
<p>Values represent the mean and standard deviation of cytokines and chemokines concentrations (pg/1...
<p>Values are expressed as mean ± SEM from 8–14 mice per group. *P <0.05, **P <0.01, ***P<0.001 in c...
<p>DR1 and B10 mice were infected intranasally with NC or PR8 or were mock-infected with PBS. Mice w...
<p>Mice infected with BC7/PBS or BC7/alginate were sacrificed at specified times, and the cytokine l...
a<p>Cytokines and chemokines are expressed as pg/ml (mean±SEM).</p>b<p>Significant difference of <i>...
<p>Lung levels of TNF-α (A and B), IL-1β (C and D) and IL-6 (E and F) of wild type (WT, black bars) ...
<div><p>(A) IFN-γ enzyme-linked immunosorbent assay was performed on lung homogenates with four mice...
<p>Mice were infected intranasally with 5×10<sup>7</sup> CFU WT GBS and cytokine levels in cell-free...
<p>Cytokine levels from infected lungs (n = 3 mice per virus group, days 1 and 4 post-inoculation (p...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>Groups of three BALB/c mice were inoculated intranasally with 10<sup>5</sup> pfu of SD16 or SD16-...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>C57BL/6 mice were inoculated with PBS (mock) or infected intranasally with 10<sup>5</sup> PFU inf...
<p>C57BL/6 (B6) or B6.C3H-<i>sst1</i> congenic mice were infected with <i>C. pneumoniae</i> (Cp) as ...
<p>Mice were euthanized at indicated times p.i. The collected lungs were weighed, and 10% homogenate...
<p>Values represent the mean and standard deviation of cytokines and chemokines concentrations (pg/1...
<p>Values are expressed as mean ± SEM from 8–14 mice per group. *P <0.05, **P <0.01, ***P<0.001 in c...
<p>DR1 and B10 mice were infected intranasally with NC or PR8 or were mock-infected with PBS. Mice w...
<p>Mice infected with BC7/PBS or BC7/alginate were sacrificed at specified times, and the cytokine l...
a<p>Cytokines and chemokines are expressed as pg/ml (mean±SEM).</p>b<p>Significant difference of <i>...
<p>Lung levels of TNF-α (A and B), IL-1β (C and D) and IL-6 (E and F) of wild type (WT, black bars) ...
<div><p>(A) IFN-γ enzyme-linked immunosorbent assay was performed on lung homogenates with four mice...
<p>Mice were infected intranasally with 5×10<sup>7</sup> CFU WT GBS and cytokine levels in cell-free...