Production of pro-inflammatory cytokines/chemokines are upregulated by SEA in HTR8 cells.

<p>The first-trimester cell line model, HTR8/SVneo, was treated with SEA (25 ug/ml) for 24 h. Media from all treatment conditions was collected and measured for cytokine expression. <b>A and B</b>) IL-6 & IL-8 production are both increased after SEA exposure. <i>P</i> = 0.01 and 0.02, respectively, n = 9 <b>C</b>) MCP1 production is increased after SEA treatment. <i>P</i><0.04, n = 13 pairs of HTR8 cells cultured +/− SEA.