HTR8 cells increase pro-inflammatory cytokine production in response to plasma from schistosome-infected pregnant women.

<p>The first-trimester cell line, HTR8/SVneo, was cultured in serum-free media with the addition of 10% plasma from women with schistosomiasis or uninfected women at 32 weeks of gestation. Culture supernatants from cells with cultured with plasma from infected women had higher levels of A) IL-6, <i>P</i><0.02 and B) IL-8. <i>P</i><0.01. n = 58 (29/group). Median and IQR presented.