<p>In each plot, the histogram represents the genome-wide distribution (11,000 samples) of the fraction of SNPs in each locus with F<sub>ST</sub> higher than the 99% genome-wide upper boundary (black line) this distribution is plotted against the high- F<sub>ST</sub> ratio for each CD risk locus bin in this analysis ordered from smallest to largest. Dots above the line represent loci with significantly elevated high- F<sub>ST</sub> ratios (P<0.05). Raw data for CD regions is found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0070564#pone.0070564.s001" target="_blank">Table S1</a>. a. within Africa, b. within East Asia, c. within Europe, d. between Europe/East Asia, e. between Africa/East Asia, f. between Africa/E...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
<p>Risk-allele frequencies (RAF) were shown as heights of bars across the 11 HapMap populations at 1...
The XP‐EHH values are plotted in the CR1 gene region including 50kb upstream and downstream for each...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p>The frequencies of six cross-ethnic T2D risk alleles were shown as dark blue wedges across the 53...
<p>Combined association scores were computed using Mantel Haenszel X<sup>2</sup> test, following imp...
<p>(A): Fst among the three populations vs minor allele frequencies (MAF). Big green dot and triangl...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>Plots are constructed using phased haplotypes for a. <i>East Asians</i>, b. <i>Europeans</i>, c. ...
<p>We identified 12 common diseases with five or more independent cross-ethnic risk alleles from Var...
<p>Similar with <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002621#p...
The branch length of endemic population group are plotted in the CR1 gene region including 50kb upst...
<p><i>P</i>-values, gene organization, and linkage disequilibrium (LD) plots according to the chromo...
<p>Black line shows number of SNPs per 100 kb window. Centromere locations are indicated by grey sha...
<p>Plots depict genotyped SNPs in the extended HLA region of chromosome 6 with top ranking SNPs mark...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
<p>Risk-allele frequencies (RAF) were shown as heights of bars across the 11 HapMap populations at 1...
The XP‐EHH values are plotted in the CR1 gene region including 50kb upstream and downstream for each...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p>The frequencies of six cross-ethnic T2D risk alleles were shown as dark blue wedges across the 53...
<p>Combined association scores were computed using Mantel Haenszel X<sup>2</sup> test, following imp...
<p>(A): Fst among the three populations vs minor allele frequencies (MAF). Big green dot and triangl...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>Plots are constructed using phased haplotypes for a. <i>East Asians</i>, b. <i>Europeans</i>, c. ...
<p>We identified 12 common diseases with five or more independent cross-ethnic risk alleles from Var...
<p>Similar with <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002621#p...
The branch length of endemic population group are plotted in the CR1 gene region including 50kb upst...
<p><i>P</i>-values, gene organization, and linkage disequilibrium (LD) plots according to the chromo...
<p>Black line shows number of SNPs per 100 kb window. Centromere locations are indicated by grey sha...
<p>Plots depict genotyped SNPs in the extended HLA region of chromosome 6 with top ranking SNPs mark...
Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequenc...
<p>Risk-allele frequencies (RAF) were shown as heights of bars across the 11 HapMap populations at 1...
The XP‐EHH values are plotted in the CR1 gene region including 50kb upstream and downstream for each...