<p>Plots are constructed using phased haplotypes for a. <i>East Asians</i>, b. <i>Europeans</i>, c. <i>Hispanics</i> and d. <i>African-Americans</i> and illustrate breakdown of LD with increasing distances from a core proximal <i>TNFSF4</i> SNP and are approximately to scale. The core is located at the <i>TNFSF4</i> gene-5′ boundary (black circle) and is selected as the most proximal 5′ marker, <i>rs1234314</i>, in each population. Gene location is depicted to scale; we have additionally labelled each plot to show the location of <i>rs1234317</i> and <i>rs2205960</i>, the best-associated markers from the meta-analysis.</p
<p>LD plots are presented for African-American controls (A and B) and for European-American/Argentin...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>Haplotype circle size is proportional to its frequency. Each haplotypes is numbered. Haplotypes t...
<p>This section of chromosome 1q25.1 encompasses the <i>TNFSF4</i> gene and upstream region as defin...
<p><b>A</b>) <b>Bayesian Phylogram</b> (K80+G, 50% Majority-Rule Consensus Tree), with Bayesian Post...
<p>Circles represent haplotypes and connecting lines represent patterns of relationship. Hash marks ...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p>In each plot, the histogram represents the genome-wide distribution (11,000 samples) of the fract...
<p>The size of the circles indicates the haplotype frequency. Mutation number for every node (>5 for...
(a) CYTB; (b) ND4; (c) PCB; (d) TOPO; (e) URO; (f) ZNFP. Ticks on branches indicate mutational steps...
<p>Frequency data for SNPs in CFTR (<u>Panel A</u>) or NF1 (<u>Panel B</u>) were collated for each o...
Each circle represents a haplotype and its size is proportional to haplotype frequency. Colors indic...
<p>Each node represents one mutational step and the size of each circle represents the frequency of ...
<p>Points represent the location of alleles, while corresponding lines indicate the average length o...
<p>The sampled haplotypes are indicated by circles; the geographical regions from which the sample w...
<p>LD plots are presented for African-American controls (A and B) and for European-American/Argentin...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>Haplotype circle size is proportional to its frequency. Each haplotypes is numbered. Haplotypes t...
<p>This section of chromosome 1q25.1 encompasses the <i>TNFSF4</i> gene and upstream region as defin...
<p><b>A</b>) <b>Bayesian Phylogram</b> (K80+G, 50% Majority-Rule Consensus Tree), with Bayesian Post...
<p>Circles represent haplotypes and connecting lines represent patterns of relationship. Hash marks ...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p>In each plot, the histogram represents the genome-wide distribution (11,000 samples) of the fract...
<p>The size of the circles indicates the haplotype frequency. Mutation number for every node (>5 for...
(a) CYTB; (b) ND4; (c) PCB; (d) TOPO; (e) URO; (f) ZNFP. Ticks on branches indicate mutational steps...
<p>Frequency data for SNPs in CFTR (<u>Panel A</u>) or NF1 (<u>Panel B</u>) were collated for each o...
Each circle represents a haplotype and its size is proportional to haplotype frequency. Colors indic...
<p>Each node represents one mutational step and the size of each circle represents the frequency of ...
<p>Points represent the location of alleles, while corresponding lines indicate the average length o...
<p>The sampled haplotypes are indicated by circles; the geographical regions from which the sample w...
<p>LD plots are presented for African-American controls (A and B) and for European-American/Argentin...
<p>The upper panel indicates the alternative alleles in different grey shades, and the defined ~167 ...
<p>Haplotype circle size is proportional to its frequency. Each haplotypes is numbered. Haplotypes t...