Effects of CCI on mEPSC rates and amplitudes recorded from EGFP-labeled, GABAergic neurons.

<p>Representative traces of mEPSCs at a holding potential of -75 mV in sham- (<b>A</b>) and CCI-treated (<b>B</b>) animals (scale bar: 10 s; 50 pA). (<b>C</b>) CCI treated mice exhibited a reduced rate in mEPSCs recorded from GABAergic neurons (n = 34) as compared to sham-operated animals (n = 26 neurons; *** P < 0.001, Mann-Whitney rank sum test). Data: mean ± s.e.m. (<b>D</b>) Corresponding cumulative probability plot of inter-event-intervals of mEPSCs. (<b>E</b>) Amplitudes of mEPSCs were not significantly changed in CCI treated mice (n = 34 neurons) as compared to sham control (n = 26 neurons, P>0.1, Mann-Whitney rank sum test). Data: mean ± s.e.m. (<b>F</b>) Corresponding cumulative probability plot of mEPSC amplitudes.