<i>LacZ</i> expression controlled by PPARγ conserved sequences 1-5 reflects the tissue-specific pattern of endogenous PPARγ expression.

<p>(<b>A</b>) Tissue distribution of <i>LacZ</i> mRNA expression in PPARγ (+/−) and PPARγ CS1-5_<i>LacZ</i> line 1 transgenic mice (5 weeks, n = 3), evaluated by RT-qPCR. Error bars denote mean ± S.D. (<b>B</b>) Western blot analysis of β-galactosidase and PPARγ levels in tissues of PPARγ CS1-5_<i>LacZ</i> line 1 mice (7 weeks, n = 2). An extract of HEK-293T cells expressing exogenous β-galactosidase served as positive control.