Anti-LOS IgG antibody responses induced by MAP1-MPL immunization.

<p>32 BALB/c mice were immunized intraperitoneally (ip) with MAP1 emulsified with MPL and boosted four times at 3-week intervals. <b><i>A.</i></b> Total anti-LOS IgG antibody levels at wk 5, 8,11 and 14 following immunization. <b><i>B.</i></b> Post-immunization (wk 14) anti-LOS IgG subclass, IgM and IgA anti-LOS antibody levels. <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003559#s2" target="_blank">Results</a> are represented as box plots; the spots represent outliers beyond the 1.5 IQR (intraquartile range). IgG subclass responses indicate a T_H1-biased response (see text, <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003559#ppat.1003559-Scott1" target="_blank">[22]</a>).