Immunization with VMP001-NPs elicits Th1/Th2 balanced antibody responses.
- James J. Moon (204208)
- Heikyung Suh (333607)
- Mark E. Polhemus (252069)
- Christian F. Ockenhouse (201973)
- Anjali Yadava (333608)
- Darrell J. Irvine (333609)
Publication date
February 2013
DOIAbstract
<p>(A) C57Bl/6 mice were immunized <i>s.c.</i> on days 0 and 21 with 25 µg of MPLA and 1 µg of VMP001 in either soluble or VMP001-NP formulations, and anti-VMP001 IgG sera were characterized on days 35 and 120 for (A) IgG, (B) IgG<sub>1</sub>, (C) IgG<sub>2b</sub>, (D) IgG<sub>2c</sub>, and (E) IgG<sub>3</sub> titers.</p
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