Hepatic infiltration of Macrophages are obserbed in DSS-treated RAG-2^−/− mice.

<p>(<b>A</b>) H&E specimens of colon from mice treated with water (left) or 4% DSS (right). Magnification, ×100 (<b>B</b>) H&E specimens of liver from water- (left) and DSS-treated (right) mice. Magnification, ×200 (<b>C</b>) The number of liver mononuclear cells for each group of mice. (<b>D</b>) Proportion and (<b>E</b>) absolute number of PDCA-1⁺CD11b⁻CD11c^int pDCs and CD11b⁺CD11c⁻ macrophages among whole mononuclear cells. Data are representative of two independent experiments. Values are presented as the mean ± SEM for each group (<i>n</i> = 4, water-treated group; <i>n</i> = 4, DSS-treated group). *<i>P</i><0.05. N.S., no significant difference.