Deletion of Fn14 inhibits accumulation of progenitor cells after PH.

<p>Fn14 KO mice and wild type (WT) mice underwent PH. Expression of progenitor markers was evaluated at various time points by (A) qRT-PCR analysis, (B) Immunohistochemistry and (C) Western blot. Mean +/− SEM results from all mice (n = 5/time point) are graphed relative to baseline, pre-PH (time 0) in WT group, * p<0.05 vs time 0, # p<0.05 vs WT. Representative images of 48 hours post-PH liver are displayed (magnification 40×).