TWEAK is required for optimal liver regeneration after PH.

<p>TWEAK KO mice, WT mice and WT mice that were treated with anti-TWEAK antibodies underwent PH. Expression of progenitor markers was evaluated at various time points by (A) qRT-PCR analysis and (B) Immunohistochemistry. Mean +/− SEM results from all mice (n = 5/time point) are graphed relative to baseline, pre-PH (time 0) in WT group, * p<0.05 vs time 0, # p<0.05 vs WT. Representative images of 48 hours post-PH liver are displayed (magnification 20×).