Behavior of mice in each group in the elevated plus maze test.

<p>Data are shown as mean ± SEM for the elevated plus maze test (control, n = 10; LS group, n = 12; MDR group, n = 6). (A) illustrates the time that mice spent in the aversive open arms of the maze during 5 min of the test. (B) illustrates the time that mice spent in the closed arms of the maze during the test. (C) illustrates the number of crossings observed during the test. (D) illustrates the time that mice spent in the center of the maze during the test. (*) represents a significant individual difference when compared to the normal group (p<0.05, Mann-Whitney U test). (†) represents a significant individual difference when compared to the LS group (p<0.05, Mann-Whitney U test).