Elevated plus-maze test.

<p>a) Activity-related measures exemplified as the path length covered during the test. Bars represent the median values and the dots represent the data of each individual animal. b) Anxiety-related behavior measured as the proportion of time spent in open arms. Serotonintransporter knockout mice (5-HTT <i>KO</i>, n = 17) were less active and spent a lower proportion of time on open arms indicating increased anxiety compared to wild-type (5-HTT <i>WT</i>, n = 14) mice. Statistics: Wilcoxon exact rank sum test: ** = P<0.01, *** = P<0.001.