Behavior of mice in each group in the light-dark transition test.

<p>Data are shown as mean ± SEM for the light-dark transition test (control, n = 7; LS group, n = 11; MDR group, n = 7). (A) illustrates the time that mice spent in the light compartment during 5 min of the test. (B) illustrates the time that mice spent in the dark compartment during the test. (C) illustrates the time spent prior to the first entry to the light compartment. (D) illustrates the number of crossings between the light and dark compartments during the test. (*) represents a significant individual difference when compared to the normal group (p<0.05, Mann-Whitney U test).