K562 cellular proliferation is decreased in the presence of troglitazone and 9-<i>cis</i>-RA.

<p>Cells were cultured with vehicle (<i>white bar</i>), 1 μM 9-<i>cis-</i>RA (<i>black bar</i>), 15 μM troglitazone (<i>gray bar</i>), or 15 μM and 1 μM troglitazone and 9-<i>cis</i>-RA (<i>hatched bar</i>), respectively, for 72 hrs. BrdU incorporation was assessed by ELISA and proliferation values were normalized using Percent Vehicle = (Abs_(treatment)/Abs_(vehicle)) X 100. Results are shown as means ± SD, n = 6, LSD was used to test for differences among groups. Means followed by the same letter are not significantly different (P = 0.01).