<p>A: Specific productivity of rht-PA. B: Log fold change of mRNA of rht-PA. ▪ Condition 37°C; □ Condition 33°C.</p
<p>The two protein preparations, 400 nM each were pre-incubated at indicated temperatures and furthe...
Culture conditions that affect product quality are important to the successful operation and optimiz...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...
Mild hypothermia condition in mammalian cell culture technology has been one of the main focuses of ...
Reduced culture temperature is an increasingly popular practice to improve recombinant protein yield...
Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human th...
<p>ANOVA and the Tukey’s test. Statistical significance was considered for p<0.05. <sup>a</sup>: Sig...
<p>The AmE-711 line had been transferred 12 times and incubated for 7 days at different temperatures...
In the biopharmaceutical sector, Chinese hamster ovary (CHO) cells have become the host of choice to...
(Black) 20 mM glucose; (Dark grey) 30 mM glucose; (Light grey) 40 mM glucose.</p
Shifting an exponentially growing culture of E. coli from 37 to 10$\sp\circ$C, a temperature just ab...
Perfusion processes provide high productivity, low product residence times and consistent culture c...
<p>(A) Chase analysis of the hKv1.5 expression, cultured at 37°C or 28°C for the indicated times aft...
At the laboratory scale, sudden step increases from 30 to 42°C can be readily accomplished when expr...
<div><p>Recombinant proteins are widely used as biopharmaceuticals, but their production by mammalia...
<p>The two protein preparations, 400 nM each were pre-incubated at indicated temperatures and furthe...
Culture conditions that affect product quality are important to the successful operation and optimiz...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...
Mild hypothermia condition in mammalian cell culture technology has been one of the main focuses of ...
Reduced culture temperature is an increasingly popular practice to improve recombinant protein yield...
Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human th...
<p>ANOVA and the Tukey’s test. Statistical significance was considered for p<0.05. <sup>a</sup>: Sig...
<p>The AmE-711 line had been transferred 12 times and incubated for 7 days at different temperatures...
In the biopharmaceutical sector, Chinese hamster ovary (CHO) cells have become the host of choice to...
(Black) 20 mM glucose; (Dark grey) 30 mM glucose; (Light grey) 40 mM glucose.</p
Shifting an exponentially growing culture of E. coli from 37 to 10$\sp\circ$C, a temperature just ab...
Perfusion processes provide high productivity, low product residence times and consistent culture c...
<p>(A) Chase analysis of the hKv1.5 expression, cultured at 37°C or 28°C for the indicated times aft...
At the laboratory scale, sudden step increases from 30 to 42°C can be readily accomplished when expr...
<div><p>Recombinant proteins are widely used as biopharmaceuticals, but their production by mammalia...
<p>The two protein preparations, 400 nM each were pre-incubated at indicated temperatures and furthe...
Culture conditions that affect product quality are important to the successful operation and optimiz...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...