<p>ANOVA and the Tukey’s test. Statistical significance was considered for p<0.05. <sup>a</sup>: Significant differences respect to counterpart culture at different T°; <sup>b</sup>: Significant differences respect to CC; <sup>c</sup>: Significant differences respect to TM; <sup>d</sup>: Significant differences respect to TM/ERAD I.</p
One of the key goals in process development for monoclonal antibodies is to improve productivity and...
<p>The AmE-711 line had been transferred 12 times and incubated for 7 days at different temperatures...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...
<p>A: Specific productivity of rht-PA. B: Log fold change of mRNA of rht-PA. ▪ Condition 37°C; □ Con...
Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human th...
Mild hypothermia condition in mammalian cell culture technology has been one of the main focuses of ...
In the biopharmaceutical sector, Chinese hamster ovary (CHO) cells have become the host of choice to...
Batch cultures were grown in YPDX 6%/3% for 96 hours. Measurements are averages from three biologica...
A history of sporadically poor culture performance in the inoculum train and subsequent production c...
<p>The cultures of R27T were established in a shake flask and 7.5 L (working volume: 5 L), or 30 L (...
(Black) 20 mM glucose; (Dark grey) 30 mM glucose; (Light grey) 40 mM glucose.</p
<p>Rates are shown in µmol (gDW h)<sup>−1</sup>. Negative rates represent consumption and positive r...
Culture conditions that affect product quality are important to the successful operation and optimiz...
<p><sup>a</sup>H stands for hexose, depending on the culture’s conditions it can be either glucose (...
Background Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins wi...
One of the key goals in process development for monoclonal antibodies is to improve productivity and...
<p>The AmE-711 line had been transferred 12 times and incubated for 7 days at different temperatures...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...
<p>A: Specific productivity of rht-PA. B: Log fold change of mRNA of rht-PA. ▪ Condition 37°C; □ Con...
Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human th...
Mild hypothermia condition in mammalian cell culture technology has been one of the main focuses of ...
In the biopharmaceutical sector, Chinese hamster ovary (CHO) cells have become the host of choice to...
Batch cultures were grown in YPDX 6%/3% for 96 hours. Measurements are averages from three biologica...
A history of sporadically poor culture performance in the inoculum train and subsequent production c...
<p>The cultures of R27T were established in a shake flask and 7.5 L (working volume: 5 L), or 30 L (...
(Black) 20 mM glucose; (Dark grey) 30 mM glucose; (Light grey) 40 mM glucose.</p
<p>Rates are shown in µmol (gDW h)<sup>−1</sup>. Negative rates represent consumption and positive r...
Culture conditions that affect product quality are important to the successful operation and optimiz...
<p><sup>a</sup>H stands for hexose, depending on the culture’s conditions it can be either glucose (...
Background Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins wi...
One of the key goals in process development for monoclonal antibodies is to improve productivity and...
<p>The AmE-711 line had been transferred 12 times and incubated for 7 days at different temperatures...
Abstract We evaluated the combined effect of decreasing the temperature to a mild hypothermia range ...