Comparison of cytokines produced by mDC subsets in response to RSV vs. hMPV.

<p>(<b>A</b>) BDCA-1⁺ and (<b>B</b>) BDCA-3⁺ mDCs were isolated and incubated with RSV, hMPV or media alone for 40 hours. Cytokine and chemokine levels were measured in cell-free supernatant by multiplex assay. Data represents the mean + SEM of the fold change (infected/uninfected) in cytokine production by RSV vs. hMPV-infected mDCs from 6 donors. Linear data is reported on a logarithmic scale. The dotted line represents a 2 fold induction. Grey bars = RSV-infected cells, white bars = hMPV-infected cells. *<i>p≤0.05</i> between RSV and hMPV-infected mDCs as calculated by paired t-test.