Knockdown of Ror2 by shRNA inhibits the increase in MFU numbers mediated by Wnt5a but not by Wnt3a.

<p>(A) Expression of <i>Ror2</i> mRNA measured by qPCR in mammospheres infected with control vector shControl or knockdown vector shRor2. (B) Wild-type mammosphere cells were infected with shRor2 or shControl lentiviral vectors and treated with or without 200 ng/ml Wnt5a. Secondary mammospheres were counted one week after plating. (C) Wild-type mammospheres infected with shRor2 or shControl lentiviral vector were treated with and without 200 ng/ml. **p<.01. Error bars show 95% confidence intervals.